ETNK1 MUTATIONS INDUCE A MUTATOR PHENOTYPE THAT CAN BE REVERTED WITH PHOSPHOETHANOLAMINE

ETNK1 mutations induce a mutator phenotype that can be reverted with phosphoethanolamine

ETNK1 mutations induce a mutator phenotype that can be reverted with phosphoethanolamine

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ETNK1 mutations are recurrent in leukemia but how they contribute to oncogenesis Plant Cages is still unclear.Here, the authors show that ETNK1 mutations Tools increase mitochondrial activity, ROS and H2AX levels and that these effects can be rescued upon phosphoethanolamine supplementation.

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